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Denaturation of a protein results in the loss of its native conformation and its biological activity. Which statement best describes what happens to a protein when it is denatured?


A) Peptide bonds are broken.
B) New amino acids are joined to the peptide backbone.
C) Secondary,tertiary,and quaternary levels of structure are disrupted.
D) The N-terminal and C-terminal ends of the protein are hydrolyzed by enzymes.

E) None of the above
F) A) and D)

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Hydrogen bonding is possible between the side chains of the amino acids tyrosine and threonine.

A) True
B) False

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Which statement about oxytocin and vasopressin is not true?


A) Oxytocin and vasopressin each contain nine amino acids.
B) Oxytocin and vasopressin each contain cysteine on both sides of a disulfide bond.
C) Oxytocin and vasopressin each contain a single disulfide bond.
D) Oxytocin and vasopressin each contain cysteine as the C-terminal amino acid.

E) B) and C)
F) A) and D)

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Which conditions are commonly diagnosed by measuring the levels of specific enzymes in the blood?


A) Heart attack
B) High blood pressure
C) Pregnancy
D) Migraines

E) All of the above
F) A) and B)

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D-Amino acids have the -NH3+ group on the left side in the Fischer projection.

A) True
B) False

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What is the strongest type of interaction between two cysteine amino acid side chains in a protein?


A) Hydrogen bonding
B) London dispersion forces
C) Disulfide bond
D) Electrostatic interactions

E) A) and B)
F) None of the above

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A ________ is a peptide that contains four amino acids joined together by three peptide bonds.

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There are ________ amino acids that occur naturally in proteins.


A) 12
B) 15
C) 20
D) 21
E) 30

F) All of the above
G) A) and C)

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Which choice is the unique structural feature of collagen?


A) α-coil
B) β-sheet
C) Disulfide linkage
D) Triple helix

E) None of the above
F) A) and B)

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A diet of rice and tofu provides all essential amino acids.

A) True
B) False

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What is the C-terminal amino acid in the tetrapeptide glycylalanyisoleucylmethionine?


A) Alanine
B) Glycine
C) Methionine
D) Isoleucine

E) B) and C)
F) A) and D)

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What is the N-terminal amino acid in the tetrapeptide glycylalanyisoleucylmethionine?


A) Alanine
B) Glycine
C) Methionine
D) Isoleucine

E) None of the above
F) All of the above

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The "cartoon" shown is an example of competitive inhibition. The  cartoon  shown is an example of competitive inhibition.

A) True
B) False

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The amide bonds in peptides and proteins are called peptide bonds.

A) True
B) False

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Proteins are long chains of amino acids joined together by peptide bonds. Which structure properly depicts the peptide bond formed between two generic amino acids?


A) Proteins are long chains of amino acids joined together by peptide bonds. Which structure properly depicts the peptide bond formed between two generic amino acids? A)    B)    C)    D)
B) Proteins are long chains of amino acids joined together by peptide bonds. Which structure properly depicts the peptide bond formed between two generic amino acids? A)    B)    C)    D)
C) Proteins are long chains of amino acids joined together by peptide bonds. Which structure properly depicts the peptide bond formed between two generic amino acids? A)    B)    C)    D)
D) Proteins are long chains of amino acids joined together by peptide bonds. Which structure properly depicts the peptide bond formed between two generic amino acids? A)    B)    C)    D)

E) C) and D)
F) A) and D)

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Serine exists primarily in its neutral form at a pH ~ 6.

A) True
B) False

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Which amino acid is a basic amino acid?


A) Serine
B) Arginine
C) Cysteine
D) Alanine

E) None of the above
F) C) and D)

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What type of intermolecular forces exist between the side chains of glutamic acid and lysine?


A) Electrostatic attraction
B) London dispersion forces
C) Hydrogen bond
D) Disulfide bond

E) A) and C)
F) A) and B)

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No one plant source has sufficient amounts of all of the essential amino acids.

A) True
B) False

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The difference between normal hemoglobin and sickle cell hemoglobin is that a single amino acid of both β subunits is changed from glutamic acid to ________.

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